# Ionis Pharmaceuticals, Inc. (IONS) — Gross Profit

## Annual Gross Profit (USD)

| Year | Gross Profit |
| --- | --- |
| 2025 | $928M |
| 2024 | $694M |
| 2023 | $779M |
| 2022 | $573M |
| 2021 | $800M |
| 2020 | $717M |
| 2019 | $1.12B |
| 2018 | $598M |
| 2017 | $514M |
| 2016 | $373M |

## Quarterly Gross Profit (USD)

| Quarter | Gross Profit |
| --- | --- |
| 2026-03-31 | $243M |
| 2025-09-30 | $154M |
| 2025-06-30 | $448M |
| 2025-03-31 | $130M |
| 2024-09-30 | $133M |
| 2024-06-30 | $221M |
| 2024-03-31 | $117M |
| 2023-09-30 | $142M |
| 2023-06-30 | $186M |
| 2023-03-31 | $129M |
| 2022-09-30 | $158M |
| 2022-06-30 | $129M |
| 2022-03-31 | $138M |
| 2021-09-30 | $130M |
| 2021-06-30 | $123M |
| 2021-03-31 | $109M |
| 2020-09-30 | $157M |
| 2020-06-30 | $143M |
| 2020-03-31 | $131M |
| 2019-09-30 | $167M |
| 2019-06-30 | $162M |
| 2019-03-31 | $296M |
| 2018-09-30 | $145M |
| 2018-06-30 | $118M |

Source: [MarketCapTrends](https://marketcaptrends.com/company/IONS/gross-profit)